Pharmaceutical Business

Japan

Information Provision Activities

Information Provision Activities

New drugs are delivered to patients after passing a long process that includes basic research, clinical studies and review by the government for regulatory approvals. Even after drug products are launched and used by a large number of patients, safety and efficacy are continually checked resulting in safe and secure, useful pharmaceuticals. It is only after proper usage has been established based on safety and efficacy information that the pharmaceuticals can fulfill their desired function of contributing effectively to human health requirements.
At Sumitomo Pharma, we collect and share safety information and provide the requisite and specialized information to medical professionals via our MRs (Medical Representatives) and multiple media outlets. Our aim is to earn greater confidence among medical professionals and to contribute to the betterment of healthcare and fuller lives of patients through daily information provision activities.

Focus Areas for the Japan Business

Focus Areas for the Japan Business

In Japan, we collect and provide professional information primarily in the Psychiatry & Neurology, Diabetes, and Rare diseases areas.
In the Psychiatry & Neurology area, we have therapeutic drugs for Parkinson's disease and schizophrenia and we aim to contribute to the treatment of psychiatric and neurological diseases as a medical partner.
In the Diabetes area, we offer several drugs with different mechanisms of action and respond to a wide range of medical needs.

Product Lineup

Major Pharmaceutical Products Therapeutic Indication
TRERIEF® Therapeutic agent for Parkinson's disease
LATUDA® Atypical antipsychotic
LONASEN® Tape Atypical antipsychotic
Equa® Therapeutic agent for type 2 Diabetes
EquMet® Therapeutic agent for type 2 Diabetes
SUREPOST® Therapeutic agent for type 2 Diabetes
METGLUCO® Therapeutic agent for type 2 Diabetes
TWYMEEG® Therapeutic agent for type 2 Diabetes
AmBisome® Therapeutic agent for systemic fungal infection
REMITCH® Therapeutic agent for pruritus
Agalsidase Beta BS I.V. Infusion [JCR] Therapeutic agent for Fabry disease
IZCARGO® Recombinant Therapeutic for Mucopolysaccharidosis Type II

Research and Development

Research and Development

With a focus on the Psychiatry & Neurology and Oncology disease areas, where unmet medical needs are high, the Sumitomo Pharma Group will make the utmost of the experience and knowledge that we have acquired so far to continue making active efforts for research and development of pharmaceuticals, regenerative medicine/cell therapy, non-pharmaceutical products, and otherwise. In other areas, too, we will tap into assets at hand and make steady R&D efforts to deliver solid value to patients.

Psychiatry and Neurology

We are promoting competitive drug discovery research based on our proprietary drug discovery platforms established by continuously incorporating cutting-edge technologies. For psychiatric disorders, including schizophrenia, depression, and psychiatric symptoms related to neurological disorders, we aim to create innovative therapeutic agents that meet unmet medical needs through drug discovery based on neural circuit pathology, whereas for neurological disorders, including dementia, Parkinson's disease, and rare diseases, we seek to develop drugs for radical treatments of neurodegenerative diseases and other indications through drug discovery based on molecular pathological mechanisms. Every effort is being made to raise the success rate of research and development by applying the wealth of knowledge gained from clinical data of our products and development candidates, to translational research and by selecting appropriate drug discovery targets and biomarkers through the use of big data, such as genome information, brain waves, and imaging data.
In FY2017, we introduced a new Research Project System, under which researchers who have devised project themes take the lead in their projects up to the initial clinical development stage as a general rule.
In the development stages, the Company is working closely with its U.S. subsidiaries under the global clinical development framework to expedite the receipt of approvals from regulatory authorities by efficiently promoting clinical development according to strategic development planning.

Oncology

We have created multiple distinctive development pipelines as we gained a diverse array of knowledge to fortify drug discovery through our research and development efforts thus far. We leverage these unique pipelines to continue focusing on research and development of drugs in the Oncology area, where unmet medical needs are high.
For drug discovery, we aim to create innovative new drugs as we enhance our competitive edge by exploring new modalities with our proprietary technologies and conducting joint research with universities and research institutions.
In the development stage, we seek to improve the success rate for several products in our development pipeline that are under initial clinical evaluations by, for example, carefully assessing data in short-term, small-scale studies to identify cancer types optimally treated by them and determine the value of such products. In particular, we are concentrating our resources on TP-3654 and DSP-5336, aiming for obtaining an early approval.

Other Areas

We tap into assets at hand and make steady R&D efforts to deliver solid value to patients. 
・For GEMTESA® (therapeutic agent for overactive bladder), we steadily proceed with application for approval of its additional indication for the treatment of overactive bladder in men with benign prostatic hyperplasia (BPH) in the U.S. and application for approval for overactive bladder in Europe, China, and Taiwan. 
・To contribute to global health and precautions against future pandemics, we are engaged in research and development for the treatment of antimicrobial resistance (AMR), malaria vaccines, and a universal influenza vaccine.

Non-pharmaceutical modalities

Regenerative medicine / Cell therapy

We are promoting multiple research and development projects with a view toward early commercializing of our pipeline assets by developing a unique growth model wherein we pursue advanced industrialization/manufacturing technologies and state-of-the-art science through open innovation strategy. While steadily advancing projects in the Neurology and Ophthalmology areas, we are setting our sights on global opportunities in Japan, the U.S., and other Asian countries, plotting a trajectory for the development of next-generation regenerative medicine, including organ regeneration. We are planning to make the business pillars of its earnings during the next Mid-term Business Plan period beginning from FY2028.

Frontier Business

Anticipating the advent of an era in which it will be difficult to achieve the required level of well-being through pharmaceuticals alone, we are promoting frontier business with the aim of providing new healthcare solutions other than pharmaceuticals while also utilizing digital transformation (DX) technologies. In a bid to create synergies with our pharmaceuticals business, we will focus on the areas of mental resilience (preventing deterioration of neuropsychiatric disorders by detecting the signs at an early stage) and active aging (improving, maintaining, and enhancing the health of the elderly from their state of mind). By developing our business foundations, which include core technologies (information, engineering, or otherwise) and networks (alliances, venture capital investment, etc.), we are planning to make the business pillars of its earnings during the next Mid-term Business Plan period beginning from FY2028.

Pharmaceuticals Production

Pharmaceuticals Production

We have built a stable supply structure for our products, which are manufactured mainly at our own plants in Japan and also in collaboration with partners in Japan and other countries. Our plants have worked hard to increase the precision of their production plans by strengthening collaboration with the Sales & Marketing Division, the International Business Management Department, overseas subsidiaries, and business partners. We have also made proactive efforts such as double sourcing of active pharmaceutical ingredients and optimizing the supply chains regarding the formulation and packaging of products. To further strengthen our competitiveness, we continuously work on cost reduction activities, as well as actively striving to increase productivity in our plants, such as by reducing lead times.

Suzuka Plant

The Suzuka Plant is Sumitomo Pharma's core formulation plant, equipped with integrated pharmaceutical manufacturing facilities capable of a full range of operations from the production of active pharmaceutical ingredients to the formulation and packaging of products. It includes a state-of-the-art solid dosage formulation facility fully compliant with cGMP (the latest U.S. GMP) and supplies products globally.

Oita Plant

The Oita Plant is Sumitomo Pharma's principal facility for the production of active pharmaceutical ingredients and its equipment is cGMP-compliant. It operates 24 hours a day, 365 days a year to ensure stable production of active pharmaceutical ingredients.

USA

USA

Sumitomo Pharma America, Inc. is engaged in R&D, manufacturing and sales of pharmaceuticals.
Sumitomo Pharma America, Inc. launched in July 2023, through consolidation the functions and human resources of seven U.S. group companies, Sunovion Pharmaceuticals Inc., Sumitomo Pharma America Holdings, Inc., Sumitomo Pharma Oncology, Inc., Sumitovant Biopharma, Inc., Myovant Sciences, Inc., Urovant Sciences, Inc., and Enzyvant Therapeutics, Inc.

Sumitomo Pharma America, Inc. Product Lineup

Major Pharmaceutical Products Therapeutic Indication
ORGOVYX® Therapeutic agent for advanced prostate cancer
MYFEMBREE® Therapeutic agent for uterine fibroids and endometriosis
GEMTESA® Therapeutic agent for overactive bladder (OAB)
APTIOM® Antiepileptic
RETHYMIC® Cultured thymus tissue for pediatric congenital athymia
LATUDA® Atypical antipsychotic

China

China

Sumitomo Pharma (Suzhou)Co., Ltd. is engaged in manufacturing (subdivided packaging) and sales of pharmaceuticals.

Sumitomo Pharma (Suzhou)Co., Ltd. Product Lineup

Major Pharmaceutical Products Therapeutic Indication
MEPEM® (Brand name in Japan: MEROPEN®) Carbapenem antibiotic
ALMARL® (Brand name in Japan: Arotinolol Hydrochloride) Therapeutic agent for hypertension, angina pectoris and arrhythmia
LONASEN® Atypical antipsychotic
LATUDA® Atypical antipsychotic